Read our Nature paper revealing an unexpected role for adenosine on PKA signaling in the striatum

Written By Michael Muniak

Locomotion activates PKA through dopamine and adenosine in striatal neurons.
↗ 10.1038/s41586-022-05407-4
↗ OHSU News

“Our results suggest that acute adenosine accumulation interplays with dopamine release to orchestrate protein kinase A (PKA) activity in striatal spiny projection neurons (SPNs) and proper striatal function during animal locomotion.”

Congrats to Lei and the rest of the team!

Michael Muniak
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Our cAMPFIRE sensors are now published in Nature Methods!